Injuries of the extremities, trunk, head or neck can lead to disruption of the skin integrity . The skin damages can be so deep that  a skin cell regeneration and restoration may not possible. In these cases a skin graft can be transplanted from other body areas in order to cover and lead to the healing of chronic and complex wounds. The skin graft will be taken from the  thighs, buttocks or other body areas using a dermatome (a special surgical instrument used to cut thin slices of skin). Then the harvested skin will be meshed to stretch into a larger patch and cover a greater area and finally brought  on the recipient area (wound)  that was earlier surgically cleaned of any dead tissue, foreign matter or bacterial contamination using  a surgical scalpel, spoon and saline or diluted antiseptic material. Skin grafting produces no complications to the donor site (the thigh for example) since  only an upper part of the skin was removed allowing a following skin regeneration originating  from the deeper skin layers. A split-thickness skin graft (STSG) includes the superficial layers of the epidermis whereas the full- thickness skin graft (FTSG) includes the entire thickness of the epidermis. The spit-thickness skin graft is often used in burn injuries. For the face and hand areas we prefer the use of full thickness skin grafts because they are quite stable and do not shrink like the split thickness skin grafts can. Skin grafting is recommended for areas that are sufficiently perfused  and covered with soft tissue (e. g. muscle). For  areas that are under great mechanical stress other surgical procedures for defect coverage should be considered (flap surgery).

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